Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Vsx2tm1(DTA)Kash
Name:	visual system homeobox 2; targeted mutation 1, Kamal Sharma
MGI ID:	MGI:3835936
Synonyms:	chx10LNL-DTA, Chx10-lnl-DTA
Gene:	Vsx2  Location: Chr12:84616602-84642231 bp, + strand  Genetic Position: Chr12, 39.28 cM
Alliance:	Vsx2tm1(DTA)Kash page

Germline Transmission:	Earliest citation of germline transmission: J:145621
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready, Inserted expressed sequence) Mutations:    Insertion, Intragenic deletion   Mutation details: 176 bases of exon 1 containing the translation initiation site were replaced with a floxed STOP cassette followed by a cDNA for the diphtheria toxin A. Removal of the floxed STOP cassette is necessary for expression of DTA. (J:145621)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Vsx2 Mutation:	23 strains or lines available

Original:	J:145621 Crone SA, et al., Genetic ablation of V2a ipsilateral interneurons disrupts left-right locomotor coordination in mammalian spinal cord. Neuron. 2008 Oct 9;60(1):70-83
All:	3 reference(s)