Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hrm2Btlr
Name:	lysine demethylase and nuclear receptor corepressor; mutation 2, Bruce Beutler
MGI ID:	MGI:3834982
Synonyms:	mister clean
Gene:	Hr  Location: Chr14:70789652-70810988 bp, + strand  Genetic Position: Chr14, 36.32 cM
Alliance:	Hrm2Btlr page

Strain of Origin:	C57BL/6J
Project Collection:	Beutler Mutagenetix

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: This mutation was discovered by its visible phenotype among G3 progeny of an ENU mutagenized male mouse. It comprises a G-to-A transition in the donor splice site of intron 6, one nucleotide after the exon (G-GTGAGC -> G-ATGAGC). This mutation is likely to destroy the splice site and cause skipping of out-of-frame exon 6. (J:145522) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hr Mutation:	84 strains or lines available

Original:	J:145522 Du X, et al., Record for "mister clean", updated March 4, 2009. MGI Direct Data Submission. 2009;
All:	1 reference(s)