Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ifi30tm1Cres
Name:	interferon gamma inducible protein 30; targeted mutation 1, Peter Cresswell
MGI ID:	MGI:2178559
Synonyms:	GILT-
Gene:	Ifi30  Location: Chr8:71215419-71219307 bp, - strand  Genetic Position: Chr8, 34.15 cM
Alliance:	Ifi30tm1Cres page

Germline Transmission:	Earliest citation of germline transmission: J:72708
Parent Cell Line:	W9.5/W95 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 2 though 7 were replaced with a neomycin resistance gene. Western analysis demonstrated a lack of protein in homozygous mutant animals in extracts from the lymph nodes, spleen, lung and muscle. Weak signals were detected in extracts from the kidney and liver. (J:72708)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ifi30 Mutation:	12 strains or lines available

Original:	J:72708 Maric M, et al., Defective Antigen Processing in GILT-Free Mice. Science. 2001 Nov 9;294(5545):1361-5
All:	16 reference(s)