Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Prnptm1Aag
Name:	prion protein; targeted mutation 1, Adriano Aguzzi
MGI ID:	MGI:3826443
Synonyms:	PrnpGFP
Gene:	Prnp  Location: Chr2:131751848-131780349 bp, + strand  Genetic Position: Chr2, 64.07 cM
Alliance:	Prnptm1Aag page

Germline Transmission:	Earliest citation of germline transmission: J:142638
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout, RMCE-ready, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: Cassette exchange was used to replace the entire coding region located within exon 3 with an EGFP gene. (J:142638)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prnp Mutation:	150 strains or lines available

Original:	J:142638 Heikenwalder M, et al., Lymphotoxin-dependent prion replication in inflammatory stromal cells of granulomas. Immunity. 2008 Dec;29(6):998-1008
All:	5 reference(s)