Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Batf3tm1Kmm
Name:	basic leucine zipper transcription factor, ATF-like 3; targeted mutation 1, Kenneth M Murphy
MGI ID:	MGI:3817232
Gene:	Batf3  Location: Chr1:190830611-190841140 bp, + strand  Genetic Position: Chr1, 96.28 cM, cytoband H6
Alliance:	Batf3tm1Kmm page

Germline Transmission:	Earliest citation of germline transmission: J:141064
Parent Cell Line:	MC50 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 1-2 were replaced by a floxed neomycin cassette. Cre-mediated recombination removed the neo cassette. Gene inactivation was confirmed by a lack of protein detected by immunoblot analysis of Th1 CD4+ T cells. (J:141064)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Batf3 Mutation:	17 strains or lines available

Original:	J:141064 Hildner K, et al., Batf3 deficiency reveals a critical role for CD8alpha+ dendritic cells in cytotoxic T cell immunity. Science. 2008 Nov 14;322(5904):1097-100
All:	224 reference(s)