Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Paxip1L5Jcs36
Name:	PAX interacting (with transcription-activation domain) protein 1; lethal 5 John C Schimenti 36
MGI ID:	MGI:3814327
Synonyms:	L5Jcs36
Gene:	Paxip1  Location: Chr5:27945078-27996689 bp, - strand  Genetic Position: Chr5, 13.23 cM, cytoband A3
Alliance:	Paxip1L5Jcs36 page

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: ENU mutagenesis caused a T-to-C transition resulting in a Leu857-to-Pro missense mutation in the C-terminal BRCT domain. Protein expression was markedly decreased by the mutation as determined by immunoblot analysis of embryonic fibroblasts. (J:140559)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Paxip1 Mutation:	46 strains or lines available

Original:	J:100332 Wilson L, et al., Random mutagenesis of proximal mouse chromosome 5 uncovers predominantly embryonic lethal mutations. Genome Res. 2005 Aug;15(8):1095-105
All:	3 reference(s)