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Chd7Mt
Chemically induced Allele Detail
Summary
Symbol: Chd7Mt
Name: chromodomain helicase DNA binding protein 7; metis
MGI ID: MGI:2177297
Synonyms: GENA171
Gene: Chd7  Location: Chr4:8690406-8867659 bp, + strand  Genetic Position: Chr4, 3.68 cM
Alliance: Chd7Mt page
Mutation
origin
Strain of Origin:  BALB/cAnNCrl
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Nucleotide substitutions
 
Mutation detailsA mutation in the splice acceptor site resulted in a V1688X substitution. This mutation putatively results in a protein lacking only the most C-terminal NLS, SANT, and BRK domains. (J:104123)
Inheritance:    Dominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Chd7 Mutation:  136 strains or lines available
References
Original:  J:75619 Kiernan AE, et al., ENU mutagenesis reveals a highly mutable locus on mouse Chromosome 4 that affects ear morphogenesis. Mamm Genome. 2002 Mar;13(3):142-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory