Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Prkntm2Tmd
Name:	parkin RBR E3 ubiquitin protein ligase; targeted mutation 2, Ted M Dawson
MGI ID:	MGI:4949289
Synonyms:	parkinFlx
Gene:	Prkn  Location: Chr17:11059271-12282248 bp, + strand  Genetic Position: Chr17, 7.8 cM, cytoband A3.2-A3.3
Alliance:	Prkntm2Tmd page

Germline Transmission:	Earliest citation of germline transmission: J:171058
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion     Exon 7 was floxed. (J:171058)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prkn Mutation:	54 strains or lines available

Original:	J:171058 Shin JH, et al., PARIS (ZNF746) repression of PGC-1alpha contributes to neurodegeneration in Parkinson's disease. Cell. 2011 Mar 4;144(5):689-702
All:	9 reference(s)