Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Cdk5tm1.1Lht
Name:	cyclin dependent kinase 5; targeted mutation 1.1, Li-Huei Tsai
MGI ID:	MGI:4941828
Synonyms:	Cdk5fl
Gene:	Cdk5  Location: Chr5:24623239-24628528 bp, - strand  Genetic Position: Chr5, 11.73 cM, cytoband A3-B1
Alliance:	Cdk5tm1.1Lht page

Germline Transmission:	Earliest citation of germline transmission: J:169741
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: Exons 1-5 of the targeted gene were flanked by loxP sites and a FRT-flanked neomycin cassette was placed immediately 3'. Flp-mediated recombination removed the neo cassette. (J:169741)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cdk5 Mutation:	15 strains or lines available

Original:	J:169741 Samuels BA, et al., Cdk5 promotes synaptogenesis by regulating the subcellular distribution of the MAGUK family member CASK. Neuron. 2007 Dec 6;56(5):823-37
All:	16 reference(s)