Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Ofd1tm2.1Bfra
Name:	OFD1, centriole and centriolar satellite protein; targeted mutation 2.1, Brunella Franco
MGI ID:	MGI:4882077
Synonyms:	Ofd1fl
Gene:	Ofd1  Location: ChrX:165173029-165223700 bp, - strand  Genetic Position: ChrX, 77.28 cM
Alliance:	Ofd1tm2.1Bfra page

Germline Transmission:	Earliest citation of germline transmission: J:106035
Parent Cell Line:	TBV2 (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: Exons 4 and 5 were flanked by loxP sites via homologous recombination. The FRT flanked neo cassette was removed by flp-mediated recombination. This allele was used to generate Ofd1tm1Bfra. (J:106035)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	83 assay results
In Structures Affected by this Mutation:	21 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ofd1 Mutation:	14 strains or lines available

Original:	J:106035 Ferrante MI, et al., Oral-facial-digital type I protein is required for primary cilia formation and left-right axis specification. Nat Genet. 2006 Jan;38(1):112-7
All:	7 reference(s)