Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Hoxb8-cre)1403Uze
Name:	transgene insertion 1403, University of Zurich
MGI ID:	MGI:4881836
Synonyms:	Hoxb8-Cretg+
Transgene:	Tg(Hoxb8-cre)1403Uze  Location: unknown
Alliance:	Tg(Hoxb8-cre)1403Uze page

Strain of Origin:

C57BL/6 x DBA/2

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Hoxb8-cre)1403Uze expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Hoxb8 (MGI:96189)   Mutation details: The construct contained a cre recombinase cassette and bovine poly(A) sequence inserted in-frame downstream of the Hoxb8 ATG site. Fertilized early-stage C57BL/6 x DBA/2 oocytes were injected with the linearized construct, and four founders were obtained. Founders were mated to generated transgenic lines, two of which (1403 and 1404) exhibited the expected expression pattern on a gross scale at E9.5 and E11.5. Line 1403 carries a single copy of the transgene and was characterized in detail. (J:168059)

Activity:	Tissue activity of this recombinase allele
Driver:	Hoxb8 (mouse) Summary of all recombinase alleles driven by Hoxb8. Comparative matrix view of recombinase activities Alliance mouse Hoxb8 gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

16 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:168059 Witschi R, et al., Hoxb8-Cre mice: A tool for brain-sparing conditional gene deletion. Genesis. 2010 Oct 1;48(10):596-602
All:	23 reference(s)