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Il10tm1.1Dpca
Targeted Allele Detail
Summary
Symbol: Il10tm1.1Dpca
Name: interleukin 10; targeted mutation 1.1, Dinis P Calado
MGI ID: MGI:4868700
Synonyms: IL-10iRESeGFP
Gene: Il10  Location: Chr1:130947582-130952711 bp, + strand  Genetic Position: Chr1, 56.89 cM
Alliance: Il10tm1.1Dpca page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:167006
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Reporter)
Mutation:    Insertion
 
Mutation detailsAn IRES, EGFP, and floxed neo cassette were inserted downstream of the translation stop codon. Cre-mediated recombination removed the neo cassette. (J:167006)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il10 Mutation:  44 strains or lines available
References
Original:  J:167006 Neves P, et al., Signaling via the MyD88 adaptor protein in B cells suppresses protective immunity during Salmonella typhimurium infection. Immunity. 2010 Nov 24;33(5):777-90
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory