Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ccr2tm2.1Ifc
Name:	C-C motif chemokine receptor 2; targeted mutation 2.1, Israel F Charo
MGI ID:	MGI:4868431
Synonyms:	Ccr2R, Ccr2RFP
Gene:	Ccr2  Location: Chr9:123901987-123913594 bp, + strand  Genetic Position: Chr9, 75.05 cM, cytoband F
Alliance:	Ccr2tm2.1Ifc page

Germline Transmission:	Earliest citation of germline transmission: J:166664
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: The coding region was replaced with an RFP and floxed neo cassette. Cre-mediated recombination removed the neo cassette. The absence of transcript expression was confirmed by RT-PCR. (J:166664)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

4 assay results 1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Ccr2 Mutation:	40 strains or lines available

Original:	J:166664 Saederup N, et al., Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice. PLoS One. 2010;5(10):e13693
All:	172 reference(s)