Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Wdr36tm1Erta
Name:	WD repeat domain 36; targeted mutation 1, Ernst R Tamm
MGI ID:	MGI:4868240
Gene:	Wdr36  Location: Chr18:32970241-33000008 bp, + strand  Genetic Position: Chr18, 18.13 cM
Alliance:	Wdr36tm1Erta page

Germline Transmission:	Earliest citation of germline transmission: J:167354
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion     The first 16 exons were replaced with a lacZ and floxed neo cassette. (J:167354)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wdr36 Mutation:	43 strains or lines available

Original:	J:167354 Gallenberger M, et al., Lack of WDR36 leads to preimplantation embryonic lethality in mice and delays the formation of small subunit ribosomal RNA in human cells in vitro. Hum Mol Genet. 2011 Feb 1;20(3):422-35
All:	2 reference(s)