Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm1(PDGFB)Cbet
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Christer Betsholtz
MGI ID:	MGI:4849447
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm1(PDGFB)Cbet page

Germline Transmission:	Earliest citation of germline transmission: J:138069
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Conditional ready, Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Gt(ROSA)26Sortm1(PDGFB)Cbet expresses 1 gene Knock-in expresses: Organism Expressed Gene Homolog in Mouse Note human PDGFB (5155) Pdgfb  (MGI:97528)   Mutation details: The locus was used to drive ubiquitous expression of human PDGFB preceded by a floxed neo stop-sequence. (J:138069)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:138069 Rolny C, et al., Platelet-derived growth factor receptor-beta promotes early endothelial cell differentiation. Blood. 2006 Sep 15;108(6):1877-86
All:	5 reference(s)