Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Icam4tm1Jach
Name:	intercellular adhesion molecule 4, Landsteiner-Wiener blood group; targeted mutation 1, Joel Anne Chasis
MGI ID:	MGI:3806488
Gene:	Icam4  Location: Chr9:20940728-20941892 bp, + strand  Genetic Position: Chr9, 7.69 cM, cytoband A3
Alliance:	Icam4tm1Jach page

Germline Transmission:	Earliest citation of germline transmission: J:138068
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 1 through 3 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis of erythrocyte extracts. (J:138068)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Icam4 Mutation:	8 strains or lines available

Original:	J:138068 Lee G, et al., Targeted gene deletion demonstrates that the cell adhesion molecule ICAM-4 is critical for erythroblastic island formation. Blood. 2006 Sep 15;108(6):2064-71
All:	1 reference(s)