Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Krastm2Bbd
Name:	Kirsten rat sarcoma viral oncogene homolog; targeted mutation 2, Mariano Barbacid
MGI ID:	MGI:4844115
Synonyms:	K-Raslox
Gene:	Kras  Location: Chr6:145162425-145195965 bp, - strand  Genetic Position: Chr6, 77.37 cM, cytoband G2
Alliance:	Krastm2Bbd page

Germline Transmission:	Earliest citation of germline transmission: J:161780
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion     No details provided. (J:161780)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kras Mutation:	76 strains or lines available

Original:	J:161780 Puyol M, et al., A synthetic lethal interaction between K-Ras oncogenes and Cdk4 unveils a therapeutic strategy for non-small cell lung carcinoma. Cancer Cell. 2010 Jul 13;18(1):63-73
All:	10 reference(s)