Has2tm1e(KOMP)Mbp
Targeted Allele Detail
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Symbol: |
Has2tm1e(KOMP)Mbp |
Name: |
hyaluronan synthase 2; targeted mutation 1e, Mouse Biology Program, UC Davis |
MGI ID: |
MGI:4843777 |
Gene: |
Has2 Location: Chr15:56529023-56557935 bp, - strand Genetic Position: Chr15, 23.31 cM
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IMPC: |
Has2 gene page |
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Mutant Cell Lines: |
DEPD0006_10_A01, DEPD0006_10_A02, DEPD0006_10_A04, DEPD0006_10_A05, DEPD0006_10_A06, DEPD0006_10_B05, DEPD0006_10_B06, DEPD0006_10_C01, DEPD0006_10_C02, DEPD0006_10_D01, DEPD0006_10_D04, DEPD0006_10_E05, DEPD0006_10_F05, DEPD0006_10_G01, DEPD0006_10_G02, DEPD0006_10_G04, DEPD0006_10_H03, DEPD0006_10_H06 |
Germline Transmission: |
Unknown
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Parent Cell Line: |
JM8A1.N3 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
KOMP-CSD
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutation: |
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Insertion
Vector: L1L2_Bact_P
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Mutation details: The L1L2_Bact_P cassette was inserted at position 56545970 of Chromosome 15 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:157064)
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Original: |
J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010; |
All: |
1 reference(s) |
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