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Gt(ROSA)26Sortm1(HA)Libl
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm1(HA)Libl
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Roland S Liblau
MGI ID: MGI:3803958
Synonyms: Rosa26rtm(HA)1Lib
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm1(HA)Libl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:137838
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Not Applicable)
Mutation:    Insertion
 
Mutation detailsA floxed neo cassette with a STOP preceeded by a hemagglutinin (HA) cDNA was inserted into the locus. Cre extraction of the neo-STOP cassette is necessary to acheive expression of the HA cDNA. (J:137838)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  942 strains or lines available
References
Original:  J:137838 Saxena A, et al., Cutting edge: Multiple sclerosis-like lesions induced by effector CD8 T cells recognizing a sequestered antigen on oligodendrocytes. J Immunol. 2008 Aug 1;181(3):1617-21
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory