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Ccrl2tm1Ssoz
Targeted Allele Detail
Summary
Symbol: Ccrl2tm1Ssoz
Name: C-C motif chemokine receptor-like 2; targeted mutation 1, Silvano Sozzani
MGI ID: MGI:4839219
Gene: Ccrl2  Location: Chr9:110883902-110886586 bp, - strand  Genetic Position: Chr9, 60.92 cM, cytoband F
Alliance: Ccrl2tm1Ssoz page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:165873
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe open reading frame was replaced with a neo cassette. The absence of transcript expression was confirmed by RT-PCR on immature and TNFalpha- or LPS-stimulated bone marrow-derived dendritic cells. (J:165873)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccrl2 Mutation:  16 strains or lines available
References
Original:  J:165873 Otero K, et al., Nonredundant role of CCRL2 in lung dendritic cell trafficking. Blood. 2010 Oct 21;116(16):2942-9
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory