Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Col4a1Acso
Name:	collagen, type IV, alpha 1; anterior capsular and suture opacity
MGI ID:	MGI:4822140
Gene:	Col4a1  Location: Chr8:11248423-11362826 bp, - strand  Genetic Position: Chr8, 5.53 cM
Alliance:	Col4a1Acso page

Strain of Origin:

(101/El x C3H/El)F1

Allele Type:    Chemically induced (other) Mutation:    Single point mutation   Mutation details: Male hybrid mice were injected intraperitoneally with procarbazine hydrochloride. A G to A nucleotide substitution at position 2104 (NCBI accession # NM_009931) resulted in a glycine to aspartic acid substitution at amino acid residue 658. (J:163225) Inheritance:    Dominant

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Col4a1 Mutation:	77 strains or lines available

Original:	J:24033 Kratochvilova J, et al., Dominant cataract and recessive specific-locus mutations detected in offspring of procarbazine-treated male mice. Mutat Res. 1988 Apr;198(2):295-301
All:	3 reference(s)