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Gt(ROSA)26Sortm2(CAG-EGFP)Blh
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm2(CAG-EGFP)Blh
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Brigid L Hogan
MGI ID: MGI:4820801
Synonyms: Rosa26RFGFP
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm2(CAG-EGFP)Blh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:161806
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Reporter)
Mutation:    Insertion
 
Mutation detailsThe CAG promoter drives expression of a farnesylated EGFP preceeded by a floxed neo-STOP cassette. Cre mediated recombination is required to achieve expression of the reporter cassette. (J:161806)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  942 strains or lines available
References
Original:  J:161806 Lu Y, et al., Evidence that SOX2 overexpression is oncogenic in the lung. PLoS One. 2010;5(6):e11022
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory