Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Kmt2atm1Afst
Name:	lysine (K)-specific methyltransferase 2A; targeted mutation 1, A Francis Stewart
MGI ID:	MGI:4462256
Synonyms:	Mll1A, Mll1TG
Gene:	Kmt2a  Location: Chr9:44714652-44792594 bp, - strand  Genetic Position: Chr9, 24.84 cM
Alliance:	Kmt2atm1Afst page

Germline Transmission:	Earliest citation of germline transmission: J:160215
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, Null/knockout, Reporter) Mutation:    Insertion   Mutation details: A 6.7 kb lacZ cassette flanked by FRT sites was inserted into intron 1 of the Mll1 locus and additional loxP site was inserted downstream of exon 2. (J:160215, J:317396)

Generation of the Kmt2atm1Afst allele

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kmt2a Mutation:	135 strains or lines available

Original:	J:160215 Kranz A, et al., An improved Flp deleter mouse in C57Bl/6 based on Flpo recombinase. Genesis. 2010 Aug;48(8):512-20
All:	3 reference(s)