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Sema6dtm1Kik
Targeted Allele Detail
Summary
Symbol: Sema6dtm1Kik
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D; targeted mutation 1, Hitoshi Kikutani
MGI ID: MGI:4461971
Gene: Sema6d  Location: Chr2:123931889-124509690 bp, + strand  Genetic Position: Chr2, 60.69 cM
Alliance: Sema6dtm1Kik page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:161856
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 0.6 kbp fragment containing exon 2 in which the initiation codon is found as well as exon3 was replaced by a neomycin resistance cassette. (J:161856)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sema6d Mutation:  62 strains or lines available
References
Original:  J:161856 Takamatsu H, et al., Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II. Nat Immunol. 2010 Jul;11(7):594-600
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory