Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ccna2tm1.2Pisc
Name:	cyclin A2; targeted mutation 1.2, Piotr Sicinski
MGI ID:	MGI:4461956
Synonyms:	A2delta
Gene:	Ccna2  Location: Chr3:36619014-36626299 bp, - strand  Genetic Position: Chr3, 17.67 cM
Alliance:	Ccna2tm1.2Pisc page

Germline Transmission:	Earliest citation of germline transmission: J:155178
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Cre mediated recombination removed the neo cassette and exons 2 through 7. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibroblast extracts. (J:155178)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccna2 Mutation:	15 strains or lines available

Original:	J:155178 Kalaszczynska I, et al., Cyclin A is redundant in fibroblasts but essential in hematopoietic and embryonic stem cells. Cell. 2009 Jul 23;138(2):352-65
All:	1 reference(s)