About   Help   FAQ
Pignm1Nisw
Chemically induced Allele Detail
Summary
Symbol: Pignm1Nisw
Name: phosphatidylinositol glycan anchor biosynthesis, class N; mutation 1, Lee Niswander
MGI ID: MGI:4460999
Synonyms: gnz, Gonzo, Pigmgnz
Gene: Pign  Location: Chr1:105446147-105591402 bp, - strand  Genetic Position: Chr1, 49.63 cM, cytoband D
Alliance: Pignm1Nisw page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsThis mutation is a T to A transversion in the splice donor site of intron 23 (at position 4): GTATCCTT to GTAACCTT. (J:187360)
Inheritance:    Recessive
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 9 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pign Mutation:  68 strains or lines available
References
Original:  J:187360 McKean DM, et al., Defects in GPI biosynthesis perturb Cripto signaling during forebrain development in two new mouse models of holoprosencephaly. Biol Open. 2012;1(9):874-883
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory