About   Help   FAQ
C1qtnf5tm1(KOMP)Vlcg
Targeted Allele Detail
Summary
Symbol: C1qtnf5tm1(KOMP)Vlcg
Name: C1q and tumor necrosis factor related protein 5; targeted mutation 1, Velocigene
MGI ID: MGI:4460570
Synonyms: Ctrp5 KO
Gene: C1qtnf5  Location: Chr9:44018542-44020484 bp, + strand  Genetic Position: Chr9, 24.62 cM
Alliance: C1qtnf5tm1(KOMP)Vlcg page
IMPC: C1qtnf5 gene page
Mutation
origin
Mutant Cell Lines:  12534A-D8, 12534A-G8, 12534A-H4, 12534A-H11
Germline Transmission:  Earliest citation of germline transmission: J:204812
Parent Cell Line:  VGB6 (ES Cell)
Strain of Origin:  C57BL/6NTac
Project Collection: KOMP-Regeneron
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1
 
Mutation detailsThe insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 1090bp between positions 44019058-44020147 of Chromosome 9 (Build GRCm39). The entire gene, comprising two exons, was replaced by a neomycin resistance gene and lacZ reporter cassette. RT-PCR analysis confirmed the absence of mRNA transcripts in epididymal white adipose tissue from homozygous mutant mice. (J:136110, J:237401)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 1 line available
Carrying any C1qtnf5 Mutation:  14 strains or lines available
References
Original:  J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/09/2024
MGI 6.23
The Jackson Laboratory