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Mov10l1tm1.1Jw
Targeted Allele Detail
Summary
Symbol: Mov10l1tm1.1Jw
Name: Mov10 like RISC complex RNA helicase 1; targeted mutation 1.1, Jeremy Wang
MGI ID: MGI:4457275
Synonyms: Mov10l1fl
Gene: Mov10l1  Location: Chr15:88867112-88939355 bp, + strand  Genetic Position: Chr15, 44.49 cM
Alliance: Mov10l1tm1.1Jw page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:161125
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 18 and a floxed neo cassette was inserted downstream of ezon 21. Cre mediated recombination removed the neo casette leaving exons 18 through 21 floxed. (J:161125)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mov10l1 Mutation:  46 strains or lines available
References
Original:  J:161125 Zheng K, et al., Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway. Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11841-6
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory