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Slc26a2tm1(KOMP)Mbp
Targeted Allele Detail
Summary
Symbol: Slc26a2tm1(KOMP)Mbp
Name: solute carrier family 26 (sulfate transporter), member 2; targeted mutation 1, Mouse Biology Program, UC Davis
MGI ID: MGI:4456515
Gene: Slc26a2  Location: Chr18:61329926-61344668 bp, - strand  Genetic Position: Chr18, 34.41 cM, cytoband D3
IMPC: Slc26a2 gene page
Mutation
origin
Mutant Cell Lines:  DEPD00502_3_A09, DEPD00502_3_A10, DEPD00502_3_A11, DEPD00502_3_A12, DEPD00502_3_B09, DEPD00502_3_B10, DEPD00502_3_B11, DEPD00502_3_B12, DEPD00502_3_C09, DEPD00502_3_C10, DEPD00502_3_C11, DEPD00502_3_C12, DEPD00502_3_D09, DEPD00502_3_D10, DEPD00502_3_D11, DEPD00502_3_D12, DEPD00502_3_E09, DEPD00502_3_E10, DEPD00502_3_E11, DEPD00502_3_E12, DEPD00502_3_F09, DEPD00502_3_F10, DEPD00502_3_F11, DEPD00502_3_G10, DEPD00502_3_G11, DEPD00502_3_G12, DEPD00502_3_H09, DEPD00502_3_H10, DEPD00502_3_H11, DEPD00502_3_H12
Germline Transmission:  Unknown
Parent Cell Line:  JM8A3 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: KOMP-CSD
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P
 
Mutation detailsThe insertion of the L1L2_Bact_P cassette created a deletion of size 4357 starting at position 61331173 and ending at position 61335530 of Chromosome 18 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157064)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Slc26a2 Mutation:  30 strains or lines available
References
Original:  J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory