Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nr3c1tm2.1Ljm
Name:	nuclear receptor subfamily 3, group C, member 1; targeted mutation 2.1, Louis J Muglia
MGI ID:	MGI:4456461
Synonyms:	GrloxP, Nr3c1flox, Nr3c1flox
Gene:	Nr3c1  Location: Chr18:39543598-39652474 bp, - strand  Genetic Position: Chr18, 21.09 cM
Alliance:	Nr3c1tm2.1Ljm page

Germline Transmission:	Earliest citation of germline transmission: J:97484
Parent Cell Line:	TC1/TC-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion     Cre mediated recombination removed the neo cassette leaving exons 1c through exon 2 floxed. (J:97484)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nr3c1 Mutation:	34 strains or lines available

Original:	J:97484 Brewer JA, et al., T-cell glucocorticoid receptor is required to suppress COX-2-mediated lethal immune activation. Nat Med. 2003 Oct;9(10):1318-22
All:	15 reference(s)