Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Prkntm1Jfe
Name:	parkin RBR E3 ubiquitin protein ligase; targeted mutation 1, Jian Feng
MGI ID:	MGI:4456262
Gene:	Prkn  Location: Chr17:11059271-12282248 bp, + strand  Genetic Position: Chr17, 7.8 cM, cytoband A3.2-A3.3
Alliance:	Prkntm1Jfe page

Germline Transmission:	Earliest citation of germline transmission: J:160272
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 2 was deleted. The absence of protein expression was confirmed by western blot analysis on brain extracts. (J:160272)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prkn Mutation:	54 strains or lines available

Original:	J:160272 Roth JA, et al., Parkin regulates metal transport via proteasomal degradation of the 1B isoforms of divalent metal transporter 1. J Neurochem. 2010 Apr 1;113(2):454-64
All:	1 reference(s)