Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Kcne3tm1Tjj
Name:	potassium voltage-gated channel, Isk-related subfamily, gene 3; targeted mutation 1, Thomas J Jentsch
MGI ID:	MGI:4456240
Gene:	Kcne3  Location: Chr7:99825714-99834076 bp, + strand  Genetic Position: Chr7, 54.33 cM, cytoband F1
Alliance:	Kcne3tm1Tjj page

Germline Transmission:	Earliest citation of germline transmission: J:160721
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A floxed neo cassette was inserted upstream of exon 4 and an additonal loxP site was inserted downstream of exon 4. (J:160721)

Generation of the Kcne3tm1Tjj and Kcne3tm1.1Tjj alleles

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kcne3 Mutation:	9 strains or lines available

Original:	J:160721 Preston P, et al., Disruption of the K+ channel beta-subunit KCNE3 reveals an important role in intestinal and tracheal Cl- transport. J Biol Chem. 2010 Mar 5;285(10):7165-75
All:	1 reference(s)