Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rgs4tm1.1Jlr
Name:	regulator of G-protein signaling 4; targeted mutation 1.1, John L R Rubenstein
MGI ID:	MGI:4456099
Gene:	Rgs4  Location: Chr1:169569046-169575211 bp, - strand  Genetic Position: Chr1, 76.84 cM
Alliance:	Rgs4tm1.1Jlr page

Germline Transmission:	Earliest citation of germline transmission: J:160728
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 2 through 4 and the 5' portion of exon 5 were removed by cre mediated recombination along with the neo cassette. The absence of protein expression was confirmed by western blot analysis on frontal cortex extracts. (J:160728)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rgs4 Mutation:	18 strains or lines available

Original:	J:160728 Winden KD, et al., The organization of the transcriptional network in specific neuronal classes. Mol Syst Biol. 2009;5:291
All:	2 reference(s)