Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tektm1Sato
Name:	TEK receptor tyrosine kinase; targeted mutation 1, Thomas N Sato
MGI ID:	MGI:2159358
Synonyms:	tie-2 -
Gene:	Tek  Location: Chr4:94627526-94763213 bp, + strand  Genetic Position: Chr4, 43.34 cM
Alliance:	Tektm1Sato page

Germline Transmission:	Earliest citation of germline transmission: J:26844
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: A neomycin selection cassette was inserted into exon 2, just after sequences encoding the signal pepetide. (J:26844)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	9 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tek Mutation:	92 strains or lines available

Original:	J:26844 Sato TN, et al., Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation. Nature. 1995 Jul 6;376(6535):70-4
All:	3 reference(s)