Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ednrbtm1.1Nat
Name:	endothelin receptor type B; targeted mutation 1.1, Jeremy Nathans
MGI ID:	MGI:4438377
Gene:	Ednrb  Location: Chr14:104052061-104081838 bp, - strand  Genetic Position: Chr14, 53.05 cM
Alliance:	Ednrbtm1.1Nat page

Germline Transmission:	Earliest citation of germline transmission: J:158267
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A LoxP site was inserted upstream of the start codon within the second exon of the targeted gene. A second LoxP site was placed downstream of the second exon, within the second intron. Adjacent to the second LoxP site is an Frt site left over after the excision of the PGK-neo selectable marker. (J:158267)

Generation of the Ednrbtm1.1Nat and Ednrbtm1.2Nat alleles

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ednrb Mutation:	103 strains or lines available

Original:	J:158267 Nathans J, Direct Submission for Ednrbtm1Nat. MGI Direct Data Submission 2009. 2010;
All:	7 reference(s)