Nr1h4tm1.1Auw
Targeted Allele Detail
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Symbol: |
Nr1h4tm1.1Auw |
Name: |
nuclear receptor subfamily 1, group H, member 4; targeted mutation 1.1, Johan Auwerx |
MGI ID: |
MGI:4437613 |
Gene: |
Nr1h4 Location: Chr10:89290096-89369447 bp, - strand Genetic Position: Chr10, 44.98 cM
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Alliance: |
Nr1h4tm1.1Auw page
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Germline Transmission: |
Earliest citation of germline transmission:
J:157882
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129/Sv
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: Exon 6 was floxed. An frt flanked neo cassette used for selection was removed by flp mediated recombination.
(J:157882)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Nr1h4 Mutation: |
43 strains or lines available
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Original: |
J:157882 Milona A, et al., The normal mechanisms of pregnancy-induced liver growth are not maintained in mice lacking the bile acid sensor Fxr. Am J Physiol Gastrointest Liver Physiol. 2010 Feb;298(2):G151-8 |
All: |
4 reference(s) |
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