Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nr4a2tm1.1Pcn
Name:	nuclear receptor subfamily 4, group A, member 2; targeted mutation 1.1, Pierre Chambon
MGI ID:	MGI:4437024
Synonyms:	Nr4a2tm2.1Tpe, Nurr1L2
Gene:	Nr4a2  Location: Chr2:56996845-57014018 bp, - strand  Genetic Position: Chr2, 31.66 cM
Alliance:	Nr4a2tm1.1Pcn page

Germline Transmission:	Earliest citation of germline transmission: J:157098
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 3 and a floxed neo cassette was inserted downstream of exon 3. Cre mediated recombination removed the neo cassette leaving exon 3 floxed. (J:157098)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nr4a2 Mutation:	40 strains or lines available

Original:	J:157098 Kadkhodaei B, et al., Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons. J Neurosci. 2009 Dec 16;29(50):15923-32
All:	14 reference(s)