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Pdgfctm1e(EUCOMM)Hmgu
Targeted Allele Detail
Summary
Symbol: Pdgfctm1e(EUCOMM)Hmgu
Name: platelet-derived growth factor, C polypeptide; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
MGI ID: MGI:4434983
Gene: Pdgfc  Location: Chr3:80943723-81121347 bp, + strand  Genetic Position: Chr3, 35.73 cM
IMPC: Pdgfc gene page
Mutation
origin
Mutant Cell Lines:  HEPD0543_10_A08, HEPD0543_10_A09, HEPD0543_10_B05, HEPD0543_10_B09, HEPD0543_10_C04, HEPD0543_10_C07, HEPD0543_10_F08, HEPD0543_10_F09, HEPD0543_10_G04, HEPD0543_10_G07, HEPD0543_10_G08, HEPD0543_10_G09, HEPD0543_10_H04, HEPD0543_10_H05
Germline Transmission:  Unknown
Parent Cell Line:  JM8A1.N3 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: EUCOMM
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion     Vector: L1L2_st1
 
Mutation detailsThe L1L2_st1 cassette was inserted at position 81048240 of Chromosome 3 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157065)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Pdgfc Mutation:  35 strains or lines available
References
Original:  J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory