Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Del(5D5Mit73-D5Mit351)5Jcs
Name:	deletion, Chr 5, John C. Schimenti 5; deletion, Chr 5, John C Schimenti 5
MGI ID:	MGI:3798174
Synonyms:	Del5Jcs, Hdhdf4J
Gene:	Del(5D5Mit73-D5Mit351)5Jcs  Location: Chr5:26805985-37176464 bp  Genetic Position: Chr5, Syntenic

Germline Transmission:	Earliest citation of germline transmission: J:63451
Parent Cell Line:	v6.4 (ES Cell)
Strain of Origin:	(C57BL/6J x 129S4/SvJae)F1

Allele Type:    Radiation induced Mutation:    Intergenic deletion   Del(5D5Mit73-D5Mit351)5Jcs involves 239 genes/genome features (Gm2183, Gm19446, Gm20671 ...) View all   Mutation details: Targeted insertion of thymidine kinase into the C57BL/6J derived Chromosome 5 Htt locus in the v6.4 ES cell line was followed by 400 Gy of gamma radiation, FIAU selection, and injection into C57BL/6J blastocysts. The deletion includes the full Wolf-Hirschhorn syndrome critical region. (J:63451)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

10 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Del(5D5Mit73-D5Mit351)5Jcs Mutation:	0 strains or lines available

Original:	J:63451 Schimenti JC, et al., Interdigitated deletion complexes on mouse chromosome 5 induced by irradiation of embryonic stem cells. Genome Res. 2000 Jul;10(7):1043-50
All:	5 reference(s)