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Unc93b1tm1(KOMP)Vlcg
Targeted Allele Detail
Summary
Symbol: Unc93b1tm1(KOMP)Vlcg
Name: unc-93 homolog B1, TLR signaling regulator; targeted mutation 1, Velocigene
MGI ID: MGI:3797728
Synonyms: Unc93b1tm1Vlcg
Gene: Unc93b1  Location: Chr19:3985222-3999340 bp, + strand  Genetic Position: Chr19, 3.65 cM
Alliance: Unc93b1tm1(KOMP)Vlcg page
IMPC: Unc93b1 gene page
Mutation
origin
Mutant Cell Lines:  10049A-B3, 10049A-B7, 10049A-C5, 10049A-F5, 10049A-G9, 10049A-G10
Germline Transmission:  Earliest citation of germline transmission: J:204812
Parent Cell Line:  VGB6 (ES Cell)
Strain of Origin:  C57BL/6NTac
Project Collection: KOMP-Regeneron
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1
 
Mutation detailsThe insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 13703bp between positions 3985240-3998942 of Chromosome 19 (Build GRCm39). (J:136110)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 9 assay results
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 1 line available
Carrying any Unc93b1 Mutation:  38 strains or lines available
Notes
Cell line 10049A-G9 was successfully used to make chimeric mice. Germline transmission was accomplished. J: 211069
References
Original:  J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008;
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory