Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Thap11tm1Tpz
Name:	THAP domain containing 11; targeted mutation 1, Thomas P Zwaka
MGI ID:	MGI:3797582
Synonyms:	Roninflox
Gene:	Thap11  Location: Chr8:106581764-106583582 bp, + strand  Genetic Position: Chr8, 53.05 cM, cytoband D2
Alliance:	Thap11tm1Tpz page

Germline Transmission:	Earliest citation of germline transmission: J:136306
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of the coding region and an frt-flanked neo cassette with a 5' loxP site was inserted downstream of the coding region. (J:136306)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	26 assay results 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Thap11 Mutation:	9 strains or lines available

Original:	J:136306 Dejosez M, et al., Ronin is essential for embryogenesis and the pluripotency of mouse embryonic stem cells. Cell. 2008 Jun 27;133(7):1162-74
All:	4 reference(s)