Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm1(RARA*)Clmd
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Cathy Mendelsohn
MGI ID:	MGI:4431227
Synonyms:	Gt(ROSA)RARa403, RaraDNflox
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm1(RARA*)Clmd page

Germline Transmission:	Earliest citation of germline transmission: J:157254
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129/SvEv

Allele Type:    Targeted (Conditional ready, Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Gt(ROSA)26Sortm1(RARA*)Clmd expresses 1 gene Knock-in expresses: Organism Expressed Gene Homolog in Mouse Note human RARA (5914) Rara  (MGI:97856)   Mutation details: A truncated human RARA terminating after amino acid 403 was targeted into the Rosa26 locus but remains unexpressed until a loxP flanked stop sequence is removed via Cre-mediated recombination. (J:157254)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:157254 Rosselot C, et al., Non-cell-autonomous retinoid signaling is crucial for renal development. Development. 2010 Jan;137(2):283-92
All:	14 reference(s)