Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gfi1tm1(cre)Gan
Name:	growth factor independent 1 transcription repressor; targeted mutation 1, Lin Gan
MGI ID:	MGI:4430258
Synonyms:	Gfi1cre, Gfi1-Cre
Gene:	Gfi1  Location: Chr5:107864521-107873671 bp, - strand  Genetic Position: Chr5, 52.23 cM
Alliance:	Gfi1tm1(cre)Gan page

Germline Transmission:	Earliest citation of germline transmission: J:156945
Parent Cell Line:	AB1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1+

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Gfi1tm1(cre)Gan expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Gfi1 (MGI:103170)   Mutation details: A targeting construct was used to replace the coding sequence of Gfi1 from the translation initiation codon through exon 5 with the coding sequence of cre recombinase. The cre knockin allele was generated in AB1 ES cells. (J:160668)

Activity:	Tissue activity of this recombinase allele
Driver:	Gfi1 (mouse) Summary of all recombinase alleles driven by Gfi1. Comparative matrix view of recombinase activities Alliance mouse Gfi1 gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

56 assay results 3 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gfi1 Mutation:	31 strains or lines available

Original:	J:156945 Hwang CH, et al., Role of bone morphogenetic proteins on cochlear hair cell formation: analyses of Noggin and Bmp2 mutant mice. Dev Dyn. 2010 Feb;239(2):505-13
All:	37 reference(s)