Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Foxl2tm2.1Tre
Name:	forkhead box L2; targeted mutation 2.1, Mathias Treier
MGI ID:	MGI:4430192
Synonyms:	Foxl2f, Foxl2flox
Gene:	Foxl2  Location: Chr9:98837660-98840179 bp, + strand  Genetic Position: Chr9, 51.41 cM, cytoband E4
Alliance:	Foxl2tm2.1Tre page

Germline Transmission:	Earliest citation of germline transmission: J:157008
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A targeting vector was used to insert loxP sites to flank the single coding exon of the Foxl2 locus by homologous recombination in ES cells. An FRT-flanked neomycin selection cassette introduced during recombination was removed by Flp-mediated recombination, leaving a single residual FRT site. (J:157008)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

9 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxl2 Mutation:	15 strains or lines available

Original:	J:157008 Uhlenhaut NH, et al., Somatic sex reprogramming of adult ovaries to testes by FOXL2 ablation. Cell. 2009 Dec 11;139(6):1130-42
All:	9 reference(s)