Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Kdrtm1Wag
Name:	kinase insert domain protein receptor; targeted mutation 1, Erwin F Wagner
MGI ID:	MGI:4422101
Synonyms:	Flk1lox, Flk1loxP, Vegfr2lox
Gene:	Kdr  Location: Chr5:76093487-76139118 bp, - strand  Genetic Position: Chr5, 40.23 cM
Alliance:	Kdrtm1Wag page

Germline Transmission:	Earliest citation of germline transmission: J:86207
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 1 and an frt floxed neo cassette was inserted downstream of exon 1. (J:86207, J:156986)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	42 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kdr Mutation:	71 strains or lines available

Original:	J:86207 Haigh JJ, et al., Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling. Dev Biol. 2003 Oct 15;262(2):225-41
All:	33 reference(s)