Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pgk2tm1Dao
Name:	phosphoglycerate kinase 2; targeted mutation 1, Deborah A O'Brien
MGI ID:	MGI:4421784
Gene:	Pgk2  Location: Chr17:40517909-40519500 bp, - strand  Genetic Position: Chr17, 19.44 cM
Alliance:	Pgk2tm1Dao page

Germline Transmission:	Earliest citation of germline transmission: J:156646
Parent Cell Line:	TC1/TC-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Most of the coding region was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on sperm and testis extracts. (J:156646)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Pgk2 Mutation:	28 strains or lines available

Original:	J:156646 Danshina PV, et al., Phosphoglycerate kinase 2 (PGK2) is essential for sperm function and male fertility in mice. Biol Reprod. 2010 Jan;82(1):136-45
All:	2 reference(s)