En2tm7.2Alj
Targeted Allele Detail
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Symbol: |
En2tm7.2Alj |
Name: |
engrailed 2; targeted mutation 7.2, Alexandra L Joyner |
MGI ID: |
MGI:4421416 |
Synonyms: |
En2GFPdelta |
Gene: |
En2 Location: Chr5:28370692-28377164 bp, + strand Genetic Position: Chr5, 13.94 cM
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Alliance: |
En2tm7.2Alj page
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Germline Transmission: |
Earliest citation of germline transmission:
J:156169
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: This allele was generated by inserting an EGFP-IRES-loxP-FRT sequence into the 5' UTR of the En2 locus immediately upstream of the ATG and a loxP site into the intron. An FRT-flanked neo cassette was removed by flp mediated recombination. Cre recombination deleted the En2 sequence, producing a null allele with a GFP reporter.
(J:156169)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any En2 Mutation: |
104 strains or lines available
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Original: |
J:156169 Cheng Y, et al., The Engrailed homeobox genes determine the different foliation patterns in the vermis and hemispheres of the mammalian cerebellum. Development. 2010 Feb;137(3):519-29 |
All: |
1 reference(s) |
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