Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Slc45a2uw-5Btlr
Name:	solute carrier family 45, member 2; underwhite 5 Bruce Beutler
MGI ID:	MGI:4420315
Synonyms:	june gloom, Slc45a2m5Btlr
Gene:	Slc45a2  Location: Chr15:11000807-11029319 bp, + strand  Genetic Position: Chr15, 5.4 cM
Alliance:	Slc45a2uw-5Btlr page

Strain of Origin:	C57BL/6J
Project Collection:	Beutler Mutagenetix

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: This mutation, discovered among G3 progeny of an ENU treated mouse, comprises a T to C transition at nucleotide position 22723 (Genbank genomic region NC_000081 for linear genomic sequence of Slc45a2), in the fifth of the gene's seven exons. This corresponds to nucleotide 1228 of the transcript and is predicted to result in replacement of serine by proline at amino acid position 378, in the eighth transmembrane domain of the protein (S378P). (J:86521, J:156313) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc45a2 Mutation:	55 strains or lines available

Original:	J:156313 Du X, et al., June gloom is an allele of Slc45a2 and displays pigmentation defects. MGI Direct Data Submission. 2010;
All:	4 reference(s)