Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Uqcrqtm1(KOMP)Wtsi
Name:	ubiquinol-cytochrome c reductase, complex III subunit VII; targeted mutation 1, Wellcome Trust Sanger Institute
MGI ID:	MGI:4419859
Gene:	Uqcrq  Location: Chr11:53318749-53321658 bp, - strand  Genetic Position: Chr11, 31.94 cM
IMPC:	Uqcrq gene page

Mutant Cell Lines:	EPD0406_2_A05, EPD0406_2_B07, EPD0406_2_E07, EPD0406_2_F06, EPD0406_2_G05, EPD0406_2_H05
Germline Transmission:	Unknown
Parent Cell Line:	JM8A3.N1 (ES Cell)
Strain of Origin:	C57BL/6N-Atm1Brd
Project Collection:	KOMP-CSD

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P   Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 1791 starting at position 53319743 and ending at position 53321534 of Chromosome 11 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. (J:148605, J:173534)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Uqcrq Mutation:	12 strains or lines available

Original:	J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009;
All:	2 reference(s)