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Tardbptm1Ckjs
Targeted Allele Detail
Summary
Symbol: Tardbptm1Ckjs
Name: TAR DNA binding protein; targeted mutation 1, C K James Shen
MGI ID: MGI:4418697
Synonyms: TardbpNEO
Gene: Tardbp  Location: Chr4:148696839-148711476 bp, - strand  Genetic Position: Chr4, 78.77 cM
Alliance: Tardbptm1Ckjs page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:155958
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 and 3 were flanked by loxP sites and an FRT flanked neo cassette and a 29 bp deletion for genotyping were inserted in intron 3 via homologous recombination. (J:155958)
Generation of the Tardbptm1Ckjs and Tardbptm1.1Ckjs alleles
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tardbp Mutation:  60 strains or lines available
References
Original:  J:155958 Wu LS, et al., TDP-43, a neuro-pathosignature factor, is essential for early mouse embryogenesis. Genesis. 2010 Jan;48(1):56-62
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory